Pathology and Laboratory Medicine at the University of Wisconsin

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Department Affiliations

Pathology Faculty

PhD Program Faculty Trainers

Cancer Biology Researchers

Growth Factor/Matrix Biology Researchers

Graduate Education Committee (GEC)

Cancer Biology Trainers

Growth Factor/Matrix Biology Trainers

Daniel S Greenspan, PhD

Professor

Department of Pathology and Laboratory Medicine

Email:		dsgreens@wisc.edu
Office:		5675 MSC
Phone:		608.262.4676
FAX:		None
Pager:		None

Mailing Address:

5675 MSC
1300 University Ave
Madison, WI 53706

Research Summary

Extracellular controls of cell behavior

Professional Experience

2006-Present	Professor Department of Pharmacology, University of Wisconsin, Madison, WI
1997-Present	Professor, Department of Pathology, University of Wisconsin, Madison, WI
2003-2006	Vice Chair for Research, Department of Pathology, University of Wisconsin, Madison, WI
1992-1997	Associate Professor, Department of Pathology, University of Wisconsin, Madison, WI
1986-1992	Assistant Professor, Department of Pathology, University of Wisconsin, Madison, WI

Education

1984-1986	Associate Research Scientist, Department of Genetics, Yale University
1981-1984	Postdoctoral Fellow, Department of Genetics, Yale University.
1981	Ph.D., New York University.

Selected Publications

Ge, G., and Greenspan, D. S. BMP1 Controls TGFß1 Activation Via Cleavage of Latent TGFß-binding Protein. J. Cell Biol. 175, 111-120 (2006).

Steiglitz, B. M., Kreider, J. M., Frankenburg, E. P., Pappano, W. N., Hoffman, G. G., Meganck, J A., Liang, X., Höök, M., Birk, D E., Goldstein, S. A., and Greenspan, D. S. Procollagen C-proteinase enhancer 1 genes are important determinants of the mechanical properties and geometry of bone and the ultrastructure of connective tissues. Mol. Cell. Biol. 26, 238-249 (2006).

Ge, G., Hopkins, D. R., Ho, W.-B., and Greenspan, D. S. GDF11 forms a BMP1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells. Mol. Cell. Biol. 25, 5846-5858 (2005).

Scott, I.C., Blitz, I.L., Pappano, W.N., Maas, S.A., Cho, K.W.Y., and Greenspan, D.S.: Twisted gastrulation homologs are extracellular cofactors in antagonism of BMP signaling. Nature 410, 475-478 (2001).

Kessler, E., Takahara, K., Biniaminov, L., Brusel, M., and Greenspan, D.S.: Bone Morphogenetic Protein-1: the type I procollagen C-proteinase. Science 271, 360-362 (1996).