University of Wisconsin-Madison Department of Pathology and Laboratory Medicine Graphic
Photo of Erik Ranheim, MD, PhD



Department Affiliations


 
Erik Ranheim, MD, PhD
Associate Professor (CHS)
Vice Chair of Education
Department of Pathology and Laboratory Medicine
Email: earanheim@wisc.edu
Office: K4/432 CSC
Phone: 608.263.0057
FAX: 608.265.6215
Pager: None
Mailing Address:
Box 8550 Clinical Science Center
600 Highland Avenue
Madison, WI 53792
Research Summary
Beta-catenin in normal and neoplastic lymphoid development; tumor immunology; hematopoietic and leukemic stem cell biology
Professional Experience
2003-Present Assistant Professor, Dept. of Pathology, University of Wisconsin Medical School
1999-2003 Staff Physician, Hematopathology, Stanford University School of Medicine
Education
1996 MD, University of Minnesota
1994 PhD, University of Minnesota
Selected Publications
Wu Q., Zierold C, Ranheim EA (2009) Dysregulation of Frizzled 6 is a critical component of B cell leukemogenesis in a mouse model of chronic lymphocytic leukemia. Blood 113; 3031-9.
Naive mouse macrophages beomce activated following recognition of L5178Y lymphoma cells via convurrent ligation of CD40, NKG2D, and CD18 molecules (2009). Buhtoiarov I., , Rakhmilevich A, Lanier LL, Ranheim EA and Sondel PM. J Immunol 182; 1940-53.
Wu Q.*, Buhtoiarov I.*, Sondel PM, Rakhmilevich A, and Ranheim EA (2009) Effective Immunotherapy of a Mouse Model of Chronic Lymphocytic Leukemia by CD40-Activated Macrophages. J Immunol. In press.
Kim YC, Clark RJ, Ranheim EA, and Alexander CM (2008). : Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector.. Cancer Research 68: 10145-10153.
McDermott SP*, Ranheim EA*, Leatherberry VS, Khwaja SS, Mastroianni M, Klos K and Alexander CM. (2006) Syndecan-1 null mice resist carcinogen-induced tumor development. Oncogene, 26; 1407-1416.
Ranheim EA, Kwan H, Wang, YK, Reya T, Weissman IL, and Francke U (2005). Frizzled 9 knockout mice have abnormal B cell development. Blood, 105(6):2487-94.
Clinical Interests
Hematopathology, with a particular interest in chronic lymphocytic leukemia and other B cell malignancies.