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Curriculum/Course Work

Course Work/Certification

The Program in Cellular and Molecular Pathology encourages each student to develop an independent and creative approach to science. The elective course program for a distributed minor is flexible, so that individual requirements can be tailored to the professional objectives of each student. The actual series of courses taken by each student is decided in consultation with an advisory committee consisting of the student, major professor, and four other faculty, two of whom must be trainers in the Pathology Graduate Program. New graduate students should consult with the Chair of the Graduate Education Committee, Dr. Zsuzsa Fabry, when planning their first semester coursework. The Graduate Education Committee has designed a set of guidelines to aid the students and their advisory committees in the task of constructing an appropriate series of formal course requirements. These guidelines are described below. Students should consult the Department Secretary regarding University Regulations when choosing their committee members.


Registration

Auditing:
Most courses may be audited and you will register as an auditor, ensuring class materials will be prepared for everyone. If there is limited space in the class, however, auditors must make room for fully registered students. An audited class will appear on your transcript, but will not count for credit.

Credit Load:
All students must register for 8-12 credits each semester (4-8 credits during the 8 week General Session during the summer) until dissertator status is reached. During the Fall and Spring Semester, it is advisable to sign up for enough research credits (Pathology 990) to bring the total credit load to 12 credits. This will keep the credit level above the 8 credit minimum should it become necessary to drop a course. Students who have not been assigned a major professor for the first semester should sign up for research credits under Dr. Zsuzsa Fabry. When a student chooses a laboratory and major professor, they should sign up for research credits under them.

To reach dissertator status, all course work must be completed, the Written Comprehensive Qualifying Examination (Prelim A) and the Oral Research Proposal Examination (Prelim B) passed, and the Graduate School residency requirements met. This will typically occur in the third year of study. Dissertators must register for 3 research credits each semester, including the 8 week summer session.

Web(My UW) Registration
The university utilized web-based registration through the My UW portal (my.wisc.edu), and the Registrar’s office will send all eligible students registration information. You will need a computer with Internet access, your university netID and password, a current timetable (or access to the online timetable), and your major professor’s section number for research. The major professor for incoming students will be Dr. Zsuzsa Fabry. For Pathology 990 research credits, you will receive an e-mail from the CMP Graduate Program Office with a five digit course number to register under the appropriate major professor. If you are unable to register for a course, you will have to call the department responsible for the course to obtain authorization. The department office will need your Campus ID number and your name to enter you into the system for that course listing. They will provide you with a five digit call number which you should then be able to use to register for the course.


Requirements for the Major

Candidates will be expected to have knowledge of cellular and molecular biology and pathology. Courses are chosen to provide each student with a background in the four focus areas of the program (oncology-cancer biology, cell matrix and growth factor biology, immunopathology and neuropathology) and in basic areas of biochemistry, cell and molecular biology, and genetics in preparation for in-depth study of the cellular and molecular pathogenesis of disease. The courses taken by the student to satisfy the Ph.D. requirement in the Cellular and Molecular Pathology Track are selected by the student and his/her major professor. All courses must contribute to an organized program of study and research. A Pathology Certification Form should be filed with the Pathology Graduate Education Committee Office and is used as a guide in constructing an appropriate series of formal course requirements from the individual student. These courses are then submitted to the student’s advisory committee for approval. It should be noted that guidelines for the Ph.D. established by the Graduate School must be adhered to. Credits earned in thesis research combined with formal course credits must meet the guidelines of the Graduate School.

Required Core Courses for a Major in Pathology: For the major, a minimum of 12 credits is required, including the following courses or their equivalent:

  • Pathology 803, Pathogenesis of Major Human Disease, 3 cr
  • Pathology 750, Cellular & Molecular Biology/Pathology, 3 cr
  • Pathology 809, Molecular Mechanisms of Disease, 2 cr
  • Pathology 901, Student Seminar Series, 1 cr
  • Pathology 900, Departmental Seminar Series, 0 cr
  • Professional Development Course
  • Ethics Course

Students are also required to take a minimum of one of the following topics courses or their equivalent. Students are strongly encouraged to select these courses according to their focus area of research.

  • Pathology 709, Special Topics in Immunopathology: Immune System in Health and Disease, 2 cr
  • Pathology 751, Cell and Molecular Biology of Aging, 3 cr
  • Pathology 951, Cell Matrix, Structure and Function, 2 cr

Below is a list of courses approved for the Ethics course requirement and the Professional Development course requirement. This list is not exhaustive and your advisory committee may approve a course that is not listed below to count towards either of these requirements:

Approved ethics courses:
Med Hist 545, Ethical and Regulatory Issues in Clinical Research I
, 1 cr.
Oncology 675, Appropriate Conduct and Effective Communication of Science, 1 cr
Chem 901, Seminar in Scientific Ethics, 0-1 credits
Vet Med Study Group, Good Practices in Science
Nursing 802, Ethics and the Responsible Conduct of Research 1cr

Approved statistics courses (not part of the breadth requirement):
Statistical Problems in Genetics and Molecular Biology
1 credit; Meets with Genetics 677 and Medical Genetics 677.
Biostatistics 541, Introduction to Biostatistics I, 3 cr.

Suggested professional development courses:
Life Sci Comm 560, Scientific Writing
, 3 cr.
Neuroscience 700, Professional Development for Biomedical Graduate Students, 1 cr (crosslisted with Physiology)


Requirements for Minor

Breadth Courses leading to a Distributed Minor in Pathology: In addition to the core courses outlined above, all students for the Ph.D. in the Cellular and Molecular Pathology Track will be expected to complete a minimum of 10 graduate level credits toward a distributed minor. A suggested distributed minor would consist of advanced courses from the following areas: cell and molecular biology, genetics, immunology, biochemistry, oncology, virology and statistics.

To fulfill the advanced course requirements, additional courses are required from each section listed below. These courses should provide the student and his/her committee with the flexibility to complement a broad range of disease-oriented basic research projects. New, experimental, or special topics courses that offer advanced level training in these specialty areas are acceptable. The advanced training received in these areas coupled with thesis research will insure that the Pathology Ph.D. student has proper breadth knowledge and a foundation in core areas of biochemistry, cell and molecular biology, genetics and immunology.

Biochemistry

  • Biochemistry 601 Protein & Enzyme Structure and Function 2 cr
  • Biochemistry 602 Biochemical Mechanisms of Regulation in the Cell 2 cr
  • Biochemistry 603 Eukaryotic Molecular Biology 2 cr
  • Biochemistry 612 Prokaryotic Molecular Biology 3 cr
  • Biochemistry 625 Coenzymes and Cofactors in Enzymology 2 cr
  • Biochemistry 651 Biochemical Methods 2 cr
  • Biochemistry 729 Advanced Topics 1-3 cr
  • Biomolecular Chemistry 675 Advanced or Special Topics 1 cr

Cell and Molecular Biology

  • Pathology 703 General Pathology 3 cr
  • Zoology 555 Developmental Biology Laboratory 3 cr
  • Pharmacology 710 Cytosolic and Nuclear Signaling Mechanisms 2 cr
  • Zoology 570 Cell Biology 3 cr
  • Oncology 703 Carcinogenesis & Tumor Cell Biology 3 cr
  • Bacteriology/Oncology 640 General Virology 3 cr
  • Human Oncology 410 Radiobiology 2 cr
  • Oncology 675 Special Topics in Cancer Research 2 cr
  • Human Oncology 640 Biochemical Mechanisms of Tumor Promotion and Progression 2 cr
  • Oncology 707 Growth and Differentiation 3 cr
  • Oncology 720 Advanced Molecular Virology 2 cr

Immunology

  • Biomolecular Chemistry 612 Immunochemical Techniques 2 cr
  • Medical Microbiology 528 Immunology 3 cr
  • Medical Microbiology 720 Topics in Immunology 3 cr
  • Bacteriology 790 Immunology of Infectious Disease 3 cr

Genetics

  • Genetics 466 General Genetics 3 cr
  • Medical Genetics 707 Genetics of Development 3 cr
  • Genetics 561 Introductory Cytogenetics 2-3 cr
  • Genetics/Biochemistry 640 Molecular Neurobiology 2 cr
  • Genetics 565 Human Genetics 3cr
  • Genetics 677 Advanced Topics in Genetics 1-3 cr
  • Bacteriology 607 Advanced Microbial Genetics 3 cr
  • Genetics 612 Prokaryotic Molecular Biology 3 cr

Types of Classes

Seminars: Students are required to give a minimum of 3 seminars throughout their graduate career. Seminars can be given as part of a the Pathology Seminar Series (PATH 900), a course or a regional, national, or international meeting. Additionally, dissertators are required to give a thesis-based seminar prior to their thesis defense as part of the Pathology Seminar Series, Pathology 900. A list of seminar courses that can be taken for credit is listed below. Additional equivalent seminar courses can be also taken upon approval by the Student’s Advisory Committee.

  • Biochemistry 907, Advanced Molecular Genetics
  • Biochemistry 903, Membrane Biochemistry
  • Botany/Zoology 965, Cellular and Developmental Biology
  • Bacteriology 901, Microbiology
  • Genetics 993, Seminar in Genetics
  • Oncology 901,Seminar

Additional Courses: The student’s advisory committee may require additional courses. However, there is no general departmental requirement for additional course credits.

Special topics and mini-courses: Several one credit courses are usually offered each semester. Special topic courses of interest to our graduate students are offered by many departments. Mini-courses are intended to be literature oriented seminars emphasizing reading and discussion of assigned material.

Seminar courses: Many departments offer seminar courses in which each student presents a seminar during the semester.

Tutorials: Students can arrange to take tutorials in lieu of course work. Tutorials should be arranged between the interested student and professor(s). Tutorials are not a substitute for a limited background. Careful consideration should be used as to whether formal classroom instruction in a particular area is needed prior to arranging for a tutorial in that area.

Journal Clubs: Several weekly journal clubs in special topics exist. Generally one paper is presented each week. Some are offered as formal courses; others meet informally.

Below is a list of some of the journal clubs that CMP trainers currently participate in:

  • Biotechnology Training Program Student Seminar Series
  • Cancer Biology Literature Group (every other week)
  • Cardiovascular Research Center Journal Club (Thursdays once a month)
  • Developmental Biology Journal Club (Wednesdays at noon)
  • Geriatrics Journal Club (Tuesdays at 7:30)
  • Glaucoma Research Group
  • Neuroimmunology Journal Club (Fridays at 11)
  • Immunology Research Group (Thursdays at noon)
  • MSTP Student Journal Club
  • Neurological Surgery Journal Club (bi-weekly)
  • Ophthalmology & Visual Sciences Research Colloquium (Fridays at noon)
  • Ophthalmology and Visual Sciences Grand Rounds (Fridays at 7:30)
  • Ophthalmology and Visual Sciences Retina Group (Tuesdays at 7)
  • Seminar in Cellular Biology and Cytoskeletal Dynamics
  • Stem Cell Biology Journal Club (Fridays at noon)
  • Transcriptional Mechanisms Research Group (monthly)
  • UWCCC Tumor Immunology Journal Club (Tuesdays at 9)
  • Vascular Biology Research Colloquium (monthly)
  • Zebrafish Research Group (last Tuesday of month)

Grades

Ph.D. students must maintain a B average or better in all graduate courses. Grades of BC or lower suggest an inadequate comprehension of course material. The Graduate School requires that a student maintain a minimum graduate GPA of 3.0 in all graduate-level work.

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