CMP Program Publications 2007/2008

Caroline Alexander:

McDermott, S. P., Ranheim, E. A., Leatherberry, V. S., Khwaja, S. S., Klos, K. S., and Alexander, C. M. Juvenile Syndecan-1 Null Mice Are Protected from Carcinogen-induced Tumor Development. Oncogene, 26: 1407-1416, 2007.

Paguirigan, A., Beebe, D. J., and Alexander, C. M. Simulating Mouse Mammary Gland Development: Cell Ageing and Its Relation to Stem and Progenitor Activity. Cell Prolif., 40: 106-124, 2007.

Slavik, M. A., Allen-Hoffmann, B. L., Liu, B. Y., and Alexander, C. M. Wnt Signaling Induces Differentiation of Progenitor Cells in Organotypic Keratinocyte Cultures. BMC Dev. Biol., 7: 9-16 2007.

Yu, H., Alexander, C. M., and Beebe, D. J. A Plate Reader-compatible Microchannel Array for Cell Biology Assays. Lab Chip, 7: 388-391, 2007.

Yu, H., Alexander, C. M., and Beebe, D. J. Understanding Microchannel Culture: Parameters Involved in Soluble Factor Signaling. Lab Chip, 7: 726-730, 2007.

Zheng, T., Yu, H., Alexander, C. M., Beebe, D. J., and Smith, L. M. Lectin-modified Microchannels for Mammalian Cell Capture and Purification. Biomed. Microdevices, in press, 2007 [Epub ahead of print May 22 2007].

Lynn Allen-Hoffmann:

Slavik MA, Allen-Hoffmann BL, Liu BY, Alexander CM. (2007) Wnt signaling induces differentiation of progenitor cells in organotypic keratinocyte cultures. BMC Dev. Biol. 7:9

Van Pay L, Pickart MA, Rasmussen CA, Allen-Hoffmann BL. (2008) β-catenin is required for endogenous AHR-dependent, suspension mediated induction of CYP1A1 in Hepa 1c1c7 cells. Submitted to J. Biol. Chem.

Gibson ALF, Schurr MJ, Schlosser SJ, Comer AR, Allen-Hoffmann BL. (2008) Antibiotic treatments for human skin substitutes: Mafenide acetate and neomycin sulfate-polymyxin B sulfate on human Keratinocytes in monolayer culture and human skin substitute tissue. Submitted to Ann. Surg.

Liliensiek SJ, Allen-Hoffmann BL. (2008). Overexpression of the gene defender against apopototic death (DAD1) promotes survival in human NIKS keratinocytes. Submitted to J. Biol. Chem.

Allen-Hoffmann BL, Gibson ALF, Schlosser SJ, Liliensiek SJ, Schurr MJ. (2008). Use of NIKS and autologous human keratinocytes in the creation of a chimeric bioengineered skin. Submitted to Ann. Surg.

Schurr MJ, Schlosser SJ, Gibson ALF, Rasmussen CA, Allen-Hoffmann BL. (2008). Transplantation of a cultured chimeric human skin substitute generated from NIKS and primary human keratinocytes. Submitted to Ann. Surg.

Craig Atwood:

Wung, J.K., Perry, G., Kowalski, A.., Harris, P.L.R., Bishop, G.M., Trivedi, M.A., Johnson, S.C., Smith, M.A., Denhardt, D.T. and Atwood, C.S. (2007) Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal Neurons of the Alzheimer's disease brain. Current Alzheimer Research, 4(1):67-72.

Liu, T., Wimalasena, J., Bowen, R.L. and Atwood, C.S. (2007). Luteinizing hormone receptor mediates Neuronal pregnenolone production via upregulation of steroidogenic acute regulatory protein expression. Journal of Neurochemistry, 100(5):1329-1339.

Porayette, P., Gallego, M.J., Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S. (2007). Amyloid- precursor protein expression and modulation in human embryonic Stem Cells: A novel role for human chorionic gonadotropin. Biochemical and Biophysical Research Communications, 364(3):522-527.

Bishop, G.M., Smith, M.A., LaManna, J.C., Wilson, A.C., Perry, G., Atwood, C.S. (2007). Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Report 12(6):257-266.

Carlsson, C.M., Gleason, C.E., Hess, T.M., Moreland, K.A., Blazel, H.M., Koscik, R.L., Schreiber, N.T.N., Johnson, S.C., Atwood, C.S., Puglielli, L., Hermann, B.P., McBride, P.E., Stein, J.H., Sager, M.A. and Asthana, S. Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer’s disease. Journal of Alzheimer’s Disease, [in press].

Chan, H.W., Liu, T., Verdile, G., Bishop, G.M., Haasl, R.J., Smith, M.A., Perry, G., Martins, R.N. and Atwood, C.S. Copper induces apoptosis of neuroblastoma cells via post-translational regulation of the expression of Bcl-2-family proteins and the txJ mouse is a better model of hepatic than brain Cu toxicity. International Journal of Clinical and Experimental Medicine, [in press].

Atwood, C.S. and Bowen, R.L. A multi-hit endocrine model of intrinsic adult-onset asthma. Ageing Research Reviews, [in press].

Book Chapters:
Casadesus, G., Webber, K.M., Atwood, C.S., Bowen, R.L., Perry, G., Smith, M.A. (2007). Luteinizing Hormone Mediates Alzheimer-type Changes in Neurons. In: Alzheimer’s Disease: New Advances, pp307-310, Eds. Khalid Iqbal, Bengt Winblad, Jesus Avila, Medimond.

Webber, K.M., Stocco, D.M., Casadesus, G., Bowen, R.L., Atwood, C.S., Previll, L.A., Harris, P.L.R., Zhu, X., Perry, G., Smith, M.A. (2007). Steroidogenic Acute Regulatory Protein (StAR): Evidence of Gonadotropin-induced Steroidogenesis in Alzheimer Disease. In: Alzheimer’s Disease: New Advances, pp581-584, Eds. Khalid Iqbal, Bengt Winblad, Jesus Avila, Medimond.

Webber, K.M., Casadesus, G., Atwood, C.S., Bowen, R.L., Perry, G. and Smith, M.A. (2007). Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Molecular and Cellular Endocrinology, 260-262:271-275. Epub 2006 Oct 18.

Wilson, A.C., Meethal, S.V., Bowen, R.L. and Atwood, C.S. (2007). Leuprolide acetate: a drug of diverse clinical applications. Expert Opin Investig Drugs, 16(11):1851-1863.

Grace Boekhoff-Falk:

Ebacher, D.J.S., S.V. Todi, D.F. Eberl and G. Boekhoff-Falk (2007). cut mutant Drosophila auditory organs differentiate abnormally and degenerate. Fly 1:86-94.

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath (2007). Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852.

Eberl, D.F. and G. Boekhoff-Falk (2007). Development of the Drosophila Johnston's organ. International Journal of Developmental Biology 51:679-687.

Emery Bresnick:

Lugus, J., Grass, J.A., Kim, S.-I., Bresnick, E.H., and Choi, E.H. (2007) GATA-2 functions at multiple steps during hemangioblast development and differentiation. Development 134, 393-405.

Wu, J. and Bresnick, E.H. (2007) Glucocorticoid-growth factor synergism requirement for Notch4 chromatin domain activation. Mol. Cell. Biol. 27, 2411-22.

Johnson, K.D., Boyer, M.E., Kim, S.-I., Cantor, A., and Bresnick, E.H. (2007) Friend of GATA-1-independent transcriptional repression: A novel mode of GATA-1 function. Blood 109, 5230-5233.

Wozniak, R.J., Boyer, M.E., Grass, J.A., Lee, Y.-S., and Bresnick, E.H. (2007) Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells. J. Biol. Chem. 282, 14665-14674.

Kim, S.-I., Bultman, S., Jing, H., Blobel, G.A., and Bresnick, E.H. (2007) Dissecting molecular steps in chromatin domain activation during hematopoietic development. Mol. Cell. Biol. 27, 4551-4565.

Henning, K., Schroeder, T., Schwanbeck, R., Rieber, N., Bresnick, E.H., and Just, U. (2007) Notch1 signaling and erythropoietin cooperate in erythroid differentiation of multipotent progenitor cells and upregulate -globin. Expt. Hematol. 35, 1321-1332

Lurie, L.J., Boyer, M.E., Grass, J.E., and Bresnick, E.H. (2008) Transcription factor stability as a determinant of chromatin target site occupancy. Biochem. 47, 859-869


Book Chapters:
Bresnick, E.H., Im, H., Johnson, K.D., Boyer, M.E., and Grass, J.A. (2007) Dynamic nucleoprotein structure of the beta-globin locus: Establishing a rational molecular basis for the therapeutic modulation of hemoglobin switching. The Renaissance of Sickle Cell Disease in the Human Genome Era, Imperial College Press.

Wozniak, R.J. and Bresnick, E.H. (2007) Epigenetic control of complex loci during erythropoiesis. Adv. Dev. Biol. In Press.

Wu, J. and Bresnick, E.H. (2007) Bare rudiments of Notch signaling: how receptor levels are regulated. TIBS. 32, 477-485.

Kim, S.-I., Johnson, K.D., and Bresnick, E.H. (2007) Transcriptional control of erythropoiesis: Emerging mechanisms and principles. Oncogene. 26, 6777-6794.


Presentations:
Red Cell Gordon Conference, Centre Paul Langevin, Aussois, France, May, 2007

Pacific Ocular Regenerative Biology Conference, Laguna Beach, CA, September, 2007

University of Montreal, April, 2008

21st Naito Conference (Nuclear Dynamics and RNA), Yamanashi Prefecture, Japan, June, 2008

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, March, 2007

Department of Pharmacology, University of Michigan, October, 2007

Cardinal Bernardin Cancer Center, Loyola University, March, 2008

UW Translational Hematology Seminar Series, February, 2007

UW Pathology, March, 2008

Karl Broman:

Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu, WT (2007) Spectrum of heart disease associated with murine and human GATA4 mutation. J Mol Cell Cardiol 43:677–685

Manichaikul A, Palmer AA, Sen Ś, Broman KW (2007) Significance thresholds for quantitative trait locus mapping under selective genotyping. Genetics 177:1963–1966

Petkov PM, Broman KW, Szatkiewicz JP, Paigen K (2007) Crossover interference underlies sex differences in recombination rates. Trends Genet 23:539¬–542

Peirce JL, Broman KW, Lu L, Williams RW (2007) A simple method for combining genetic mapping data from multiple crosses and experimental designs. PLoS ONE 2(10):e1036

Teuscher F, Broman KW (2007) Haplotype probabilities for multiple-strain recombinant inbred lines. Genetics 175:1267–1274

Sen Ś, Satagopan JM, Broman KW, Churchill GA (2007) R/qtlDesign: Inbred line cross experimental design. Mamm Genome 18:87–93

Lemmerhirt HL, Broman KW, Shavit JA, Ginsburg D (2007) Genetic regulation of plasma von Willebrand factor levels: QTL analysis in a mouse model. J Thromb Haemost 5:329–335

Nichols KM, Broman KW, Sundin K, Young JM, Wheeler PA, Thorgaard GH (2007) Quantitative trait loci by maternal cytoplasmic environment interaction for development rate in Oncorhynchus mykiss. Genetics 175:335–347

Will Burlingham:

Molitor, M.L., and Burlingham, W.J. 2007. Immunobiology of exposure to non-inherited maternal antigens. Front Biosci 12:3302-3311.

Xu, Q., Lee, J., Jankowska-Gan, E., Schultz, J., Roenneburg, D.A., Haynes, L.D., Kusaka, S., Sollinger, H.W., Knechtle, S.J., VanBuskirk, A.M., et al. 2007. Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance. J Immunol 178:3983-3995.

Burlingham, W.J., and Jankowska-Gan, E. 2007. Mouse strain and injection site are crucial for detecting linked suppression in transplant recipients by trans-vivo DTH assay. Am J Transplant 7:466-470.

Molitor-Dart, M.L., Andrassy, J., Kwun, J., Kayaoglu, H.A., Roenneburg, D.A., Haynes, L.D., Torrealba, J.R., Bobadilla, J.L., Sollinger, H.W., Knechtle, S.J., et al. 2007. Developmental Exposure to Noninherited Maternal Antigens Induces CD4+ T Regulatory Cells: Relevance to Mechanism of Heart Allograft Tolerance. J Immunol 179:6749-6761.

Burlingham, W.J., Love, R.B., Jankowska-Gan, E., Haynes, L.D., Xu, Q., Bobadilla, J.L., Meyer, K.C., Hayney, M.S., Braun, R.K., Greenspan, D.S., et al. 2007. IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. J Clin Invest 117:3498-3506.

Derks, R.A., Jankowska-Gan, E., Xu, Q., and Burlingham, W.J. 2007. Dendritic cell type determines the mechanism of bystander suppression by adaptive T regulatory cells specific for the minor antigen HA-1. J Immunol 179:3443-3451.

Hayney, M.S., Wiegert, N.A., Pelsue, F.L., Fohl, R.M., Jankowska-Gan, E., Love, R.B., and Burlingham, W.J. 2007. T-cell responses to hepatitis B surface antigen in lung transplant recipients. Pharmacotherapy 27:1248-1252.

Kwun, J., Hu, H., Schadde, E., Roenneburg, D., Sullivan, K.A., Demartino, J., Burlingham, W.J., and Knechtle, S.J. 2007. Altered distribution of h60 minor h antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in cxcr3 / mouse recipients. J Immunol 179:8016-8025.

Joshua Coon:

McAlister GC, Phanstiel D, Good DM, Berggren WT, Coon JJ. Implementation of Electron Transfer Dissociation on a Hybrid Linear Ion Trap-Orbitrap Mass Spectrometer. Analytical Chemistry, 2007, 79, 10, 3525-3534. *featured on the journal cover*

Khidekel N, Ficarro SB, Clark PM, Swaney DL, Rexach JE, Coon JJ, Peters EC, Hsieh-Wilson LC. Probing the Dynamics of O-GlcNAc Glycosylation in the Brain using Quantitative Proteomics. Nature Chmical Biology, 2007, 3, 6, 339-348.

Good DM, McAlister GC, Phanstiel D, Coon JJ. Performance Evaluation of Electron Transfer Dissociation. Molecular and Cellular Proteomics, in press. 2007

Williams DK, McAlister GC, Good DM, Coon JJ, Muddiman DC. A Dual Electrospray Ion Source for Electron-Transfer Dissociation on a Hybrid Linear Ion Trap-Orbitrap Mass Spectrometer. Analytical Chemistry, in press. 2007

Cameron Currie:

Little, A.E.F. & C.R. Currie (submitted). Parasites may help stabilize cooperative relationships.

Poulsen, M., Cafaro, M.J., Erhardt, D.P., Little, A.E.F., Gerardo, N.M. and Currie, C.R. (submitted) Ancient Antibiotic Use in Fungus-Growing Ants.

Little, A.E.F & C.R. Currie (in press). Indirect interaction web reveals how black yeast symbionts compromise the efficiency of antibiotic defenses in fungus-growing ants. /Ecology/

Poulsen, M., Erhardt, D.P., Molinaro, D.J., Ting-Li, L., & C.R. Currie. 2007. Antagonistic bacterial interactions help shape host-symbiont dynamics within the fungus-growing ant-microbe mutualism. /PLoS ONE /2(9): e960. doi:10.1371/journal.pone.0000960.//

Little, A.E.F. & C.R. Currie 2007. Symbiont complexity: discovery of a fifth symbiont in the attine ant-microbe symbiosis. /Biology Letters /3: 501-504.

Zhang, M., Poulsen, M, & C.R. Currie 2007. Symbiont recognition of mutualistic bacteria in /Acromyrmex/ leaf-cutting ants. /International Society of Microbial Ecology Journal /1: 313-320.

Taerum, S.J., M.J. Cafaro, A.E.F. Little, T.R. Schultz, & C.R. Currie 2007. Low host-pathogen specificity in the leaf-cutting ant-microbe symbiosis. /Proceedings of the Royal Society Series B. /274:1971–1978.

Mangone, D.M. & C.R. Currie 2007. Garden substrate beahvior in five genera of fungus-growing ants./ Canadian Entomologist /139: 841-849.

Loren Denlinger:

Denlinger, L.C., Sorkness, C.A., Chinchilli, V.M., and R.F. Lemanske, Jr. 2007. Guideline-Defining Clinical Trials of the ACRN and CARE Networks. J. Allergy Clin Immunol.119:3-11.

Korpi, N.L., Sheerar, D., Urban, C., Guadarrama, A., Schell, K and L.C. Denlinger. Standardized Method to Minimize Variability in a Functional P2X7 Flow Cytometric Assay for a Multi-Center Clinical Trial . Submitted.

Denlinger, L.C., Shi, L., Guadarrama, A., Schell, K., Green, D., Morrin, A., Hogan, K., Sorkness, R., Busse, W.W. and J.E. Gern. Attenuated P2X7 Pore Function as a Risk Factor for Viurs Induced Loss of Asthma Control. Submitted.

Denlinger, L.C., Seibold, M., Ahn, K., Shi, L., Burchard, E., and R.F. Lemanske, Jr. Association of Loss-of-Function P2RX7 Alleles with Less Airway Inflammation and Enhanced Lung Function in Asthma. In Preparation.

Arjang Djamali:

Pascual J, Samaniego MD, Torrealba JR, Odorico JS, Djamali A, Becker YT, Voss B, Leverson GE, Knechtle SJ, Sollinger HW, Pirsch JD. Antibody-Mediated Rejection of the Kidney after Simultaneous Pancreas-Kidney Transplantation. J Am Soc Nephrol. 2008 Jan 30

Rao AK, Djamali A, Korcarz CE, Aeschlimann SE, Wolff MR, Stein JH. Mitral Annular Calcification is Associated with Reduced Left Ventricular Function and Inflammation in Patients with Chronic Kidney Disease. J Am Soc Echocardiogr. 2008 Jan 8;

Smavatkul C, Pascual J, Desai AG, Samaniego M, Becker BN, Djamali A. Disease progression and outcomes in type 1 diabetic kidney transplant recipients based on posttransplantation CKD staging. Am J Kidney Dis. 2007 Oct;50(4):631-40.

Kukla A, Adulla M, Pascual J, Samaniego M, Nanovic L, Becker BN, Djamali A. CKD stage-to-stage progression in native and transplant kidney disease. Nephrol Dial Transplant. 2008 Feb;23(2):693-700. Epub 2007 Sep 19.

Pascual J, Mezrich JD, Djamali A, Leverson G, Chin LT, Torrealba J, Bloom D, Voss B, Becker BN, Knechtle SJ, Sollinger HW, Pirsch JD, Samaniego MD. Alemtuzumab induction and recurrence of glomerular disease after kidney transplantation. Transplantation. 2007 Jun 15;83(11):1429-34.

Djamali A. Oxidative stress as a common pathway to chronic tubulointerstitial injury in kidney allografts. Am J Physiol Renal Physiol. 2007 Aug;293(2):F445-55. Epub 2007 Apr 25. Review.

Pascual J, Torrealba J, Myers J, Tome S, Samaniego M, Musat A, Djamali A. Collapsing focal segmental glomerulosclerosis in a liver transplant recipient on alendronate. Osteoporos Int. 2007 Oct;18(10):1435-8. Epub 2007 Apr 3.

McKiernan SH, Tuen VC, Baldwin K, Wanagat J, Djamali A, Aiken JM. Adult-onset calorie restriction delays the accumulation of mitochondrial enzyme abnormalities in aging rat kidney tubular epithelial cells. Am J Physiol Renal Physiol. 2007 Jun;292(6):F1751-60. Epub 2007 Mar 6.

Sadowski EA, Bennett LK, Chan MR, Wentland AL, Garrett AL, Garrett RW, Djamali A. Nephrogenic systemic fibrosis: risk factors and incidence estimation. Radiology. 2007 Apr;243(1):148-57. Epub 2007 Jan 31.

Zsuzsa Fabry:

Zozulya, A. L., E. Reinke, D.C. Baiu, J. Karman, M. Sandor, Z. Fabry (2007). MIP-1? induced transmigration of dendritic cells through brain microvessel endothelium is MMP-dependent and contributes to dendritic cell maturation. J. Immunol. 178:520.

Zozulya, A. L., E. Reinke, C. Ling, M. Sandor, Z. Fabry (2007) Dendritic cells in the central nervous system: immune regulators and therapeutic targets for MS. Future Neurology. 2(1), 97-106.

Reinke, E. K., J. Lee, A. Zozulya, J. Karman, W. A. Muller, M. Sandor, and Z. Fabry. 2007. Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms. J Neuroimmunol 186:86-93.

Fleming, J., and Z. Fabry. 2007. The hygiene hypothesis and multiple sclerosis. Ann Neurol 61:85-89.

Fabry, Z., E. Reinke, A. Zozulya, M. Sandor, I. Bechmann. (2007) The dialect of immune system in the CNS: The nervous tissue as an immune compartment for T cells and dendritic cells. In: Handbook of Neurochemistry and Molecular Neurobiology. Springer. 197-222.

John Fleming:

Fleming JO, Fabry Z. The hygiene hypothesis and multiple sclerosis. Ann Neurol.61:85-89, 2007.

Rolak LA, Fleming JO. The differential diagnosis of multiple sclerosis. The Neurologist. 13:57-72, 2007.

Fleming JO, Keegan BM, Parisi JE. A 52-year-old-man with progressive left-sided weakness and white matter disease. Neurology.69:600-606, 2007.

Andreas Friedl:

Zhang D, Pier T, McNeel DG, Wilding G and Friedl A. Effects of a monoclonal anti-v3 integrin antibody on Blood vessels—A pharmacodynamic study. Invest New Drugs. 2007 Feb;25(1):49-55

Su G, Blaine SA, Qiao D, Friedl A. Shedding of syndecan-1 by stromal fibroblasts stimulates human breast cancer Cell Proliferation via FGF2 activation. J Biol Chem. 2007 May 18;282(20):14906-15

Bauer M, Eickhoff JC, Gould MN, Mundhenke C, Maass N, Friedl A. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictor of poor prognosis in human primary breast cancer. Breast Cancer Res Treat. 2007 Jun 7; [Epub ahead of print]

Ibele AR, Koplin SA, Slaughenhoupt BL, Kryger JV, Friedl A, Lund DP. Colonic adenocarcinoma in a 13-year-old with cystic fibrosis. J Pediatr Surg. 2007, 42 (10):E1-3.

Presentations
Syndecan-1 Mediates Stromal-Epithelial Interactions in Breast Cancer, Frontiers in Pharmacology, Madison, WI

Michael Fritsch:

De Jong A, Warren M, Rehrauer W, Harter J, Baraboo M, Chandra S, Pauli RM, Singer DB, Fritsch MK. Fraser syndrome: affected siblings born to non-consanguinous parents and diagnosed at autopsy. Pediatr Dev Pathol (In Press, 2008).

Weinberg AL, Carter D, Ahonen M, Alarid ET, Murdoch FE, Fritsch MK. The DNA binding domain of estrogen receptor alpha is required for high affinity nuclear interaction induced by estradiol. Biochemistry 46:8933-8942, 2007.

Lee ER, Murdoch FE, Fritsch MK. High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid. Stem Cells 25:2191-2199, 2007.

McCool KW, Xu X, Singer DB, Murdoch FE, Fritsch MK. The role of histone acetylation in regulating gene expression patterns during early embryonic stem cell differentiation. J Biol Chem 282:6696-6706, 2007.

Invited Monographs and Textbook Chapters
Fritsch MK and Singer DB. Embryonic stem (ES) cell biology. In: Advances in Pediatrics (Kappy MS ed.) vol 55, (In Press - 2008).

Perlman EJ and Fritsch MK. The female reproductive system. In: Pediatric Pathology 3rd ed. (Stocker JD, Dehner LP, & Husain AN eds.) Lippincott Williams and Wilkins, (In Press - due out late 2008 to early 2009).

Fritsch MK. Female Reproductive System. In: Potter’s Pathology of the Fetus, Infant and Child 2nd ed. (Gilbert-Barness E, Kapur R, Oligny L, Siebert JR eds.). Mosby Elsevier, 2007.

Dan Greenspan:

Bobadilla JL, Love RB, Jankowska-Gan E, Xu Q, Haynes LD, Braun RK, Hayney MS, Munoz Del Rio A, Meyer K, Greenspan DS, Torrealba J, Heidler KM, Cummings OW, Iwata T, Brand D, Presson R, Burlingham WJ, Wilkes DS. TH-17, Monokines, Collagen Type V, and Primary Graft Dysfunction in Lung Transplantation. Am J Respir Crit Care Med. 2008 Jan 3; [Epub ahead of print]

Burlingham WJ, Love RB, Jankowska-Gan E, Haynes LD, Xu Q, Bobadilla JL, Meyer KC, Hayney MS, Braun RK, Greenspan DS, Gopalakrishnan B, Cai J, Brand DD, Yoshida S, Cummings OW, Wilkes DS. IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. J Clin Invest. 2007 Nov;117(11):3498-506.

Hopkins DR, Keles S, Greenspan DS. The bone morphogenetic protein 1/Tolloid-like metalloproteinases. Matrix Biol. 2007 Sep;26(7):508-23. Epub 2007 May 18. Review.

Ge G, Fernández CA, Moses MA, Greenspan DS. Bone morphogenetic protein 1 processes prolactin to a 17-kDa antiangiogenic factor. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10010-5. Epub 2007 Jun 4.

Maertens B, Hopkins D, Franzke CW, Keene DR, Bruckner-Tuderman L, Greenspan DS, Koch M. Cleavage and oligomerization of gliomedin, a transmembrane collagen required for node of ranvier formation. J Biol Chem. 2007 Apr;282(14):10647-59. Epub 2007 Feb 8.

Jasuja R, Ge G, Voss NG, Lyman-Gingerich J, Branam AM, Pelegri FJ, Greenspan DS. Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4. J Biol Chem. 2007 Mar 23;282(12):9053-62. Epub 2007 Jan 25.

Anne Griep:

Cotroneo MS, Haag JD, Zan Y, Lopez CC, Thuwajit P, Petukhova GV, Camerini-Otero RD, Gendron-Fitzpatrick A, Griep AE, Murphy CJ, Dubielzig RR, Gould MN. Characterizing a rat Brca2 knockout model. Oncogene. 2007 Mar 8;26(11):1626-35. Epub 2006 Sep 11.

Jeff Hardin:

Hardin, J., King, R., Thomas-Virnig, C., and Raich, W.B. (2008). Zygotic loss of ZEN-4/MKLP1 results in disruption of epidermal morphogenesis in the C. elegans embryo. Dev. Dyn., in press.

Yap, A., Crampton, M.S., and Hardin, J. (2007). Making and breaking contacts: the cellular biology of cadherin regulation. Curr. Opin. Cell Biol. 19:508-514.

Stevenson, T.O., Mercer, K., Cox, E.A., Szewczyk, N.J., Conley, C.A., Hardin, J.D., and Benian, G.M. (2007). unc-94 encodes a tropomodulin in C. elegans. J. Mol. Biol. 374, 936-50.

Sheffield, M.S., Loveless, T., Hardin, J., and Pettitt, J. (2007). C. elegans Enabled exhibits novel interactions with N-WASP, Abl, and cell-cell junctions. Curr. Biol. 17, 1791-1796.

Batchelder EL, Thomas-Virnig CL, Hardin J.D., White JG. (2007). Cytokinesis is not controlled by calmodulin or myosin light chain kinase in the Caenorhabditis elegans early embryo. FEBS letters 581:4337-41.

Qadota H, Inoue M, Hikita T, Köppen M, Hardin J.D., Amano M, Moerman DG, Kaibuchi K. (2007). Establishment of a tissue-specific RNAi system in C. elegans. Gene 400:166-73.

Phillips, B. T., Kidd, A. R., 3rd, King, R., Hardin, J. and Kimble, J. (2007). Reciprocal asymmetry of SYS-1/beta-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 104: 3231-6.

Sims, P. A., and Hardin, J.D. (2007). Fluorescence-integrated transmission electron microscopy images: integrating fluorescence microscopy with transmission electron microscopy. Methods Mol Biol 369: 291-308.

Peiman Hematti:

Trivedi P, Hematti P. Simultaneous generation of CD34+ primitive hematopoietic cells and CD73+ mesenchymal Stem Cells from human embryonic Stem Cells cocultured with murine OP9 stromal cells. Exp Hematol 35(1):146-54, 2007.

Trivedi P, Hematti P. Derivation and immunological characterization of mesenchymal stromal cells from human embryonic Stem Cells. Accepted for publication in Experimental Hematology.

Hematti P. Role of mesenchymal stromal cells in solid organ transplantation. In press: Transplantation Reviews.

Anna Huttenlocher:

Huttenlocher, A. and Horwitz, A.F. (2007) Wound healing by electric potential, New England Journal of Medicine. 356: 303-4.

Nuzzi, P., Senetar, M., and Huttenlocher, A. (2007) Asymmetric localization of calpain 2 during neutrophil chemotaxis, Molecular Biology of the Cell. 18: 795-805.

Clay, H, David, JM, Beery, D, Huttenlocher, A, Lyons, S and Ramakrishnan, L. (2007) Dichotomous role of the macrophage in early tuberculosis. Cell Host Microbe. 12: 29-39. .

Mathias, JR, Dodd, ME, Walters KB, Rhodes, J, Kanki, J, Look, AT and Huttenlocher, A. (2007) Live imaging of chronic inflammation caused by mutation of zebrafish HAI-1, Journal of Cell Science, 120:3372-83.

Senetar, MA, Lokuta, MA, Nuzzi, PA, Bennin, D, Ott, V, and Huttenlocher, A. (2007) PIPKI is a novel component of the uropod and regulates cell detachment during neutrophil chemotaxis, Molecular Biology of the Cell 18: 5069-80.

Cortesio, CL, Chan KT, Perrin, BJ, Burton, NO, Zhang, S, Zhang Z and Huttenlocher, A. Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion, Journal of Cell Biology, in press. 52.

Nuzzi, P., Lokuta, M., and Huttenlocher, A. (2007) Methods to analyze neutrophil chemotaxis. Methods in Molecular Biology. 37:23-36..

Cortesio, C., Chan, K., and Huttenlocher, A. (2007) Integrins in cell migration, Methods in Enzymology.426: 47-67.

Chan, K, Cortesio, C and Huttenlocher, A. Adhesion dynamics in cell migration (book chapter), in press.

Wernimont, S, Simonson, WT, Cortesio, C and Huttenlocher, A. Adhesions ring: a structural comparison between podosomes and the immune synapse, European Journal of Cell Biology, in press.

Nizar Jarjour:

Mathur SK, Schwantes EA, Jarjour NN, Busse WW. Age-related changes in eosinophil function in human subjects. Chest. 2008 Feb;133(2):412-9.

Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Gaston BM, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Wenzel SE; for the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol. 2008 Feb;104(2):394-403. Epub 2007 Nov 8.

Liu LY, Bates ME, Jarjour NN, Busse WW, Bertics PJ, Kelly EA. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007 Oct 1;179(7):4840-8.

Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2007 Feb;119(2):405-13.

Esnault S, Fang Y, Kelly EA, Sedgwick JB, Fine J, Malter JS, Jarjour NN. Circadian changes in granulocyte-macrophage colony-stimulating factor message in circulating eosinophils. Ann Allergy Asthma Immunol. 2007 Jan;98(1):75-82.

Juan Jaume:

Haymart MR, Repplinger DJ, Leverson GE, Elson DF, Sippel RS, Jaume JC, Chen H. Higher Serum TSH Level in Thyroid Nodule Patients is Associated with Greater Risks of Differentiated Thyroid Cancer and Advanced Tumor Stage. J Clin Endocrinol Metab. 2007 Dec 26; [Epub ahead of print]

Shannon Kenney:

Bhende, P. M., Dickerson, S. J., Sun, X., Feng, W. H., and Kenney, S.C. X-box binding protein 1 (XBP-1) activates lytic Epstein-barr virus gene expression in combination with protein kinase D (PKD). Journal of Virology 81:7363-73-70, 2007.

Jones, R., Bhende, P., Jones, D., Delecluse, H. J., and Kenney, S.C. Epstein-Barr virus infection induces retinoic acid-responsive genes through induction of a retinol metabolizing enzyme, DHRS9. Journal of Biol. Chem. 282:8317-24, 2007.

Jones, RJ, Seaman, WT, Feng, WH, Barlow, E., Dickerson, S., Delecluse, H.J., and Kenney, S.C. Roles of lytic viral infection and IL-6 in early versus late passage lymphoblastoid cell lines and EBV-related lymphoproliferative disease. International Journal of Cancer 121:1274-1281, 2007.

Yu, F., Feng, J., Harada, J., Chanda, S., Kenney, S., and Ren, S. B cell terminal differentiation factor XBP-1 in duces reactivation of Kaposi’s sarcoma associated herpesvirus. FEBS lett. 581: 3485-3488, 2007.

Feng, W. H., Kraus, R. J., Dickerson, S., Lim, H., Jones, R., Yu, Z., Mertz, J. E., and Kenney, S.C. Cellular and viral factors contribute to infection by Epstein-Barr virus being highly lytic in gastric AGS cells. Journal of Virology 81: 10113-10122, 2007.

Bruce Klein:

Klein BS, Tebbets B. Dimorphism and virulence in fungi. Curr Opin Microbiol. 2007 Aug;10(4):314-9. Epub 2007 Aug 23. Review.

Nemecek JC, Wüthrich M, Klein BS. Detection and measurement of two-component systems that control dimorphism and virulence in fungi. Methods Enzymol. 2007;422:465-87.

Krajaejun T, Gauthier GM, Rappleye CA, Sullivan TD, Klein BS. Development and application of a green fluorescent protein sentinel system for identification of RNA interference in Blastomyces dermatitidis illuminates the role of septin in morphogenesis and sporulation. Eukaryot Cell. 2007 Aug;6(8):1299-309. Epub 2007 May 11.

Gauthier GM, Safdar N, Klein BS, Andes DR. Blastomycosis in solid organ transplant recipients. Transpl Infect Dis. 2007 Dec;9(4):310-7. Epub 2007 Apr 11.

Cutler JE, Deepe GS Jr, Klein BS. Advances in combating fungal diseases: vaccines on the threshold. Nat Rev Microbiol. 2007 Jan;5(1):13-28. Epub 2006 Dec 11. Review.

Wüthrich M, Filutowicz HI, Allen HL, Deepe GS, Klein BS. V beta1+ J beta1.1+/V alpha2+ J alpha49+ CD4+ T cells mediate resistance against infection with Blastomyces dermatitidis. Infect Immun. 2007 Jan;75(1):193-200. Epub 2006 Oct 9.

Stuart Knechtle:

Odorico JS, Sollinger HW, Knechtle SJ: Pancreas transplantation: the University of Wisconsin experience. In: Corry RJ, Shapiro R, eds. Pancreatic Transplantation, New York, Informa Healthcare, pp. 333-357, 2007.

Schadde E, D’Alessandro AM, Musat AI, Torrealba JR, Knechtle SJ: Donor-specific HLA-antibody-mediated humoral rejection in a liver transplant recipient fully reversed with plasmapheresis and immunoglobulin. In: Clinical Transplants 2006. PI Terasaki, Ed. Los Angeles, Terasaki Foundation Laboratory, pp. 479-482, 2007.

Xu Q, Lee J, Jankowska-Gan E, Schultz J, Roenneburg DA, Haynes LD, Kusaka S, Sollinger HW, Knechtle SJ, VanBuskirk AM, Torrealba JR, Burlingham WJ: Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance. J Immunol 2007; 178:3983-3995.

Dar WA, Knechtle SJ: CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signaling through the T-cell receptor. Immunology 2007; 120:467-485.

Schadde E, Knechtle SJ: Review: chemokines in transplantation. Transplant Rev 2007; 21:107-118.

Pascual J, Mezrich JD, Djamali A, Leverson G, Chin LT, Torrealba J, Bloom D, Voss B, Becker BN, Knechtle SJ, Sollinger HW, Pirsch JD, Samaniego MD: Alemtuzumab induction and recurrence of glomerular disease after kidney transplantation. Transplantation 2007; 83:1429-1434.

D’Alessandro AM, Knechtle SJ, Chin LT, Fernandez LA, Yagci G, Leverson G, Kalayoglu M: Liver transplantation in pediatric patients: Twenty years of experience at the University of Wisconsin. Pediatr Transplant 2007; 11:661-670.

Bonatti H, Nguyen JH, Knechtle SJ, Pruett TL: Liver transplantation 2007: where do we go from here? Curr Opin Organ Transplant 2007; 12:211-214.

Kirk AD, Cherikh WS, Ring M, Burke G, Kaufman D, Knechtle SJ, Potdar S, Shapiro R, Dharnidharka VR, Kauffman HM: Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab. Am J Transplant 2007; 2619-2625.

Molitor-Dart ML, Andrassy J, Kwun J, Kayaoglu HA, Roenneburg DA, Haynes LD, Torrealba JR, Bobadilla JL, Sollinger HW, Knechtle SJ, Burlingham WJ: Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance. J Immunol 2007; 179:6749-6761.

Kwun J, Hu H, Schadde E, Roenneburg D, Sullivan KA, DeMartino J, Burlingham WJ, Knechtle SJ: Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in Cxcr3-/- mouse recipients. J Immunol 2007; 179:8016-8025.

Youngsook Lee:

Mysliwiec, M.R., Kim, T.-G., and Lee, Y. Characterization of Zinc Finger Protein 496 that interacts with Jumonji/jarid2. FEBS letters, 581(14):2633-2640, 2007.

Wozniak R.J., Boyer, M.E., Grass, J.A., Lee, Y., and Bresnick, E.H. Context-dependent GATA factor function: Combinatorial requirements for transcriptional control in hematopoietic and endothelial cells. J of Biological Chemistry, 282(19):14665-74, 2007.

Kim, K.-H., Antkiewicz, D.S., Yan, L., Eliceiri, K.W., Heideman, W., Peterson, R.E., and Lee, Y. Lrrc10 is required for early heart development and function in zebrafish. Developmental Biology, 308:494-506, 2007.

Kim, K.-H., Kim T.-G., Micales, B., Lyons, G.E., and Lee, Y. Dynamic expression patterns of Leucine Rich Repeat containing protein 10 in the heart. Developmental Dynamics, 236:2225-2234, 2007.

Lin, B.C., Sullivan R., Lee, Y., Moran, S., Glover, E., and Bradfield, C.A. Deletion of aryl hydrocarbon receptor associated protein 9 leads to cardiac malformation and embryonic lethality. J. Biol. Chem. 282:35924-32. 2007.

Gary Lyons:

Singla, DK, Lyons, GE, and Kamp, TJ (2007) Transplanted Embryonic Stem Cells Following Mouse Myocardial Infarction Inhibit Apoptosis and Cardiac Remodeling, Am J Physiol: Heart and Circulatory Physiology, 293(2):H1308-14.

Kim, K, Kim, T, Micales, B, Lyons, GE, Lee, Y (2007) Dynamic expression patterns of Leucine Rich Repeat Containing Protein 10 in the heart. Dev. Dyn. 236(8):2225-34.

Kamp, T.J. and Lyons, GE (2007) Embryonic Stem Cells and cardiogenesis. In Cardiovascular Regeneration and Stem Cell Therapy, A. Leri, P. Anversa, W.H. Frishman eds. Blackwell Publishing. Chapter 3, pp. 25-35.

Jim Malter:

Shen ZJ, Kim SK, Jun DY, Park W, Kim YH, Malter JS, Moon BJ. (2007) Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells.Exp Cell Res. 313(7):1415-25. Epub 2007 Feb 3.

Westmark, C & Malter JS (2007). FMRP Mediates mGluR5-Dependent Translation of Amyloid Precursor Protein. PloS Biology Mar;5(3):e52.

Esnault, S, Braun RK, Shen, ZJ, Xiang Z, Heninge E, Love RB, Sandor M , Malter JS. (2007) Pin1 Modulates Type 1 Immune Responses, PLoS ONE. Feb 21;2(2):e226.

S Wang, BP Simon, DA Bennett, JA Schneider, JS Malter, DS Wang (2007), The Significance of Pin1 in the Development of Alzheimer's Disease J Alz Dis 11(1):13-23.

Esnault, S, Rosenthal LA, Shen ZJ, Sedgwick J, Szakaly RJ, Sorkness R, JS Malter, (2007) A Critical Role for Pin1 in Allergic Pulmonary Eosinophilia in Rats, JACI. Aug 24; [Epub ahead of print]

Z-J Shen, S Esnault, LA Rosenthal, RJ. Szakaly, RL Sorkness, PR. Westmark, M Sandor, JS Malter, (2008), Pin1 regulates eosinophil TGF-1 production and allergic lung fibrosis, J Clin Invest. Jan 10; [Epub ahead of print]

Esnault E, Shen ZJ, Malter JS (in press, 2008) Pinning Down Signaling in the immune System: The Role of the Peptidyl-Prolyl Isomerase Pin1 in Immune Cell Function. Crit Rev Immunology.

Esnault S, Fang Y, Kelly EA, Sedgwick JB, Fine J, Malter JS, Jarjour NN. Circadian changes in granulocyte-macrophage colony-stimulating factor message in circulating eosinophils. Ann Allergy Asthma Immunol. 2007 Jan;98(1):75-82.

S Esnault, L A Rosenthal, ZJ Shen, Cara J Westmark, R L Sorkness, JS Malter, (2008, in press), Thymic Stromal Lymphopoietin Expression in Allergic Pulmonary Inflammation is Pin1 Dependent. JACI.

JS Malter, S Esnault, L A. Rosenthal, Z-J Shen, R L Sorkness (2008, in press), Letter to the Editor, JACI.

Albee Messing:

Quinlan RA, Brenner M, Goldman J, & Messing A. GFAP and its role in Alexander disease. Experimental Cell Research 313:2077-2087, 2007.

Brew HM, Gittelman JX, Silverstein RS, Hanks T, Demas VP, Robinson LC, Robbins CA, McKee-Johnson J, Chiu SY, Messing A, & Tempel BL. Seizures and reduced lifespan in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory Neurons. J Neurophysiol 98:1501-1525, 2007.

Douglas CL, Vyazovskiy V, Southard T, Chiu SY, Messing A, Tononi G, & Cirelli C. Sleep in Kcna2 knockout mice. BMC Biology (in press)

Zou W, Kim BO, Liu Y, Messing A, & He JJ. Protection against HIV-1 Tat neurotoxicity by Ginkgo biloba extract EGb 761 involving glial fibrillary acidic protein. American Journal of Pathology (in press)

Deane Mosher:

Calzada MJ, Kuznetsova SA, Sipes JM, Rodrigues RG, Cashel JA, Annis DS, Mosher DF, Roberts DD. Calcium indirectly regulates immunochemical reactivity and functional activities of the N-domain of thrombospondin-1. Matrix Biol. 2007 Dec 15; [Epub ahead of print]

Mosher DF. Adding complexity to fibronectin-platelet interactions. Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):203-4.

Carlson CB, Lawler J, Mosher DF. Structures of thrombospondins. Cell Mol Life Sci. 2008 Jan 12; [Epub ahead of print]

Margosio B, Rusnati M, Bonezzi K, Cordes BL, Annis DS, Urbinati C, Giavazzi R, Presta M, Ribatti D, Mosher DF, Taraboletti G. Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain. Int J Biochem Cell Biol. 2007 Oct 9; [Epub ahead of print]

Barthel SR, Johansson MW, McNamee DM, Mosher DF. Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma. J Leukoc Biol. 2008 Jan;83(1):1-12. Epub 2007 Oct 10. Review.

Annis DS, Gunderson KA, Mosher DF. Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations. J Biol Chem. 2007 Sep 14;282(37):27067-75. Epub 2007 Jul 9.

Kujawski LA, Longo WL, Williams EC, Turman NJ, Brandt N, Mosher DF, Eickhoff JC, Kahl BS. A 5-drug regimen maximizing the dose of cyclophosphamide is effective therapy for adult Burkitt or Burkitt-like lymphomas. Cancer Invest. 2007 Mar;25(2):87-93.

Staniszewska I, Zaveri S, Del Valle L, Oliva I, Rothman VL, Croul SE, Roberts DD, Mosher DF, Tuszynski GP, Marcinkiewicz C. Interaction of alpha9beta1 integrin with thrombospondin-1 promotes angiogenesis. Circ Res. 2007 May 11;100(9):1308-16. Epub 2007 Apr 5.

Terry Oberley:

Nithipongvanitch R, Ittarat W, Velez JM, Zhao R, St Clair DK, Oberley TD: Evidence for p53 as guardian of the cardiomyocyte mitochondrial genome following acute Adriamycin treatment. J Histochem Cytochem 55: 629-39, 2007.

Nithipongvanitch R, Ittarat W, Cole MP, Tangpong J, St. Clair DK, Oberley TD. Mitochondrial and nuclear p53 localization in cadiomyocytes: redox modulation by doxorubicin (Adriamycin)? Antioxid Redox Signal 9: 1001-8, 2007.

Daosukho C, Chen Y, Noel T, Sompol P, Nithipongvanitch R, Velez JM, Oberley TD, St. Clair DK. Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury. Free Radic Biol Med 42: 1818-25, 2007.

Bourdeau-Heller JM, Oberley TD: Prostate carcinoma cells selected by long-term exposure to reduced oxygen tension show remarkable biochemical plasticity via modulation of superoxide, HIF-1a levels, and energy metabolism. J Cell Physiol 212(3): 744-52, 2007.

Chaiswing L, Bourdeau-Heller JM, Zhong W, Oberley TD. Characterization of redox state of two human prostate carcinoma cell lines with different degrees of aggressiveness. Free Radic Biol Med 43(2): 202-15, 2007.

Aziz MH, Manoharan HT, Church DR, Dreckschmidt NE, Zhong W, Oberley TD, Wilding G, Verma AK. Protein Kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer. Cancer Res 67: 8828-38, 2007.

Li Yafan, Wheeler DL, Ananthaswamy H, Verma AK, Oberley TD. Differential tumor biology effects of double-initiation in a mouse skin chemical carcinogenesis model comparing wild type versus protein kinase Cepsilon overexpression mice. Accepted, Toxicol Pathol 2008.

Dave O’Connor:

Wiseman RW, Wojcechowskyj JA, Greene JM, Blasky AJ, Gopon T, Soma T, Friedrich TC, O’connor SL, O’Connor DH (2007) Simian Immunodeficiency Virus SIVmac239 Infection of Major Histocompatibility Complex-Identical Cynomolgus Macaques from Mauritius. J Virol 81: 349-361.

Wojcechowskyj JA, Yant LJ, Wiseman RW, O’connor SL, O’Connor DH (2007) Control of Simian Immunodeficiency Virus SIVmac239 Is Not Predicted by Inheritance of Mamu-B*17-Containing Haplotypes. J Virol 81: 406-410.

O’connor SL, Blasky AJ, Pendley CJ, Becker EA, Wiseman RW, Karl JA, Hughes AL, O’Connor DH (2007) Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques. ImmunoGenetics

Karl, J. A., R. W. Wiseman, K. J. Campbell, A. J. Blasky, A. L. Hughes, B. Ferguson, D. S. Read, and O’Connor DH. (2008) Identification of MHC class I sequences in Chinese-origin rhesus macaques. ImmunoGenetics 60: 37-46.

Invited review manuscripts
Wiseman, R.W., O’Connor DH 2007. MHC-Defined macaques in transplantation research. Transplantation Reviews.

Bimber, B., and O’Connor DH. 2007. KIRigami: the case for studying NK cell receptors in SIV+ macaques. Immunol Research.

Donna Peters:

Maqueda A, Moyano JV, Hernández Del Cerro M, Peters DM, Garcia-Pardo A. The heparin III-binding domain of fibronectin (III4-5 repeats) binds to fibronectin and inhibits fibronectin matrix assembly. Matrix Biol. 2007 Oct;26(8):642-51. Epub 2007 Jun 14.

Chen Q, Sivakumar P, Barley C, Peters DM, Gomes RR, Farach-Carson MC, Dallas SL. Potential role for heparan sulfate proteoglycans in regulation of transforming growth factor-beta (TGF-beta) by modulating assembly of latent TGF-beta-binding protein-1. J Biol Chem. 2007 Sep 7;282(36):26418-30. Epub 2007 Jun 19.

Matyas Sandor:

Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS. Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest. 2008 Feb 1;118(2):479-490.

Reinke EK, Lee J, Zozulya A, Karman J, Muller WA, Sandor M, Fabry Z. Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms. J Neuroimmunol. 2007 May;186(1-2):86-93. Epub 2007 Apr 27.

Hogan LH, Heninger E, Elsner RA, Vonderheid HA, Hulseberg P, Co D, Sandor M. Requirements for CD4(+) T cell levels in acute Mycobacterium bovis strain bacille Calmette Guerin (BCG)-induced granulomas differ for optimal mycobacterial control versus granuloma formation. Int Immunol. 2007 May;19(5):627-33. Epub 2007 Apr 19.

Esnault S, Braun RK, Shen ZJ, Xiang Z, Heninger E, Love RB, Sandor M, Malter JS. Pin1 modulates the type 1 immune response. PLoS ONE. 2007 Feb 21;2(2):e226.

Zozulya AL, Reinke E, Baiu DC, Karman J, Sandor M, Fabry Z. Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases. J Immunol. 2007 Jan 1;178(1):520-9.

Hogan LH, Co DO, Karman J, Heninger E, Suresh M, Sandor M. Virally activated CD8 T cells home to Mycobacterium bovis BCG-induced granulomas but enhance antimycobacterial protection only in immunodeficient mice. Infect Immun. 2007 Mar;75(3):1154-66. Epub 2006 Dec 18.

Christine Seroogy:

Dahlberg PE, Schartner JM, Timmel A, Seroogy CM. Daily subcutaneous injections of peptide induce CD4+ CD25+ T regulatory cells. Clin Exp Immunol. 2007 Aug;149(2):226-34. Epub 2007 May 9.

Jartti T, Burmeister KA, Seroogy CM, Jennens-Clough ML, Tisler CJ, Salazar LP, Dasilva DF, Evans MD, Vrtis RF, Wallace PK, Ruiz-Perez B, Gangnon RE, Lemanske RF Jr, Gern JE. Association between CD4(+)CD25(high) T cells and atopy in children. J Allergy Clin Immunol. 2007 Jul;120(1):177-83. Epub 2007 Apr 16.

Schartner JM, Fathman CG, Seroogy CM. Preservation of self: an overview of E3 ubiquitin ligases and T cell tolerance. Semin Immunol. 2007 Jun;19(3):188-96. Epub 2007 Apr 2. Review.

MacKenzie DA, Schartner J, Lin J, Timmel A, Jennens-Clough M, Fathman CG, Seroogy CM. GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype. J Biol Chem. 2007 Mar 30;282(13):9696-702. Epub 2007 Jan 26.

John Sheehan

Misenheimer, T.M., Buyue, Y., and Sheehan, J.P. (2007) The Heparin-binding Exosite is Critical to Allosteric Activation of Factor IXa in the Intrinsic Tenase Complex: The role of arginine 165 and factor X. Biochemistry 46(26):7886-95.

Buyue, Y., Whinna, H., Sheehan, J.P. The Heparin-Binding Exosite of Factor IXa is a Critical Regulator of Plasma Thrombin Generation and Venous Thrombosis (submitted for publication).

Branam D, Selander KS, Chen D, Teng L, Merrell M, de Idiaquez D, Rose-John S, Sheehan J.P., and Harris KW. Cytokine receptor gp130 signaling stimulates secretion of tissue factor-expressing tumor microparticles from cancer cells (in preparation).

Nader Sheibani:

Sheibani N, Scheef EA, DiMiao TA, Kondo S, and Sorenson CM. (2007). Bcl-2 expression modulates cell adhesion and migration promoting branching of ureteric bud cells. J Cell. Physiol 210:616-625.

Albert DM, Scheef EA,Wang S, Mehraein F, Sorenson CM, Darjatmoko SR, and Sheibani N. (2007) Calcitriol is a potent inhibitor of retinal neovascularization. Invest. Ophthalmol. Vis. Sci. 48:2327-2334.

Kondo S, Scheef EA, Sheibani N, and Sorenson CM. (2007) PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am. J. Physiol. Cell. Physiol. 292:C2070-C2083.

Sattarahmady N, Moosavi-Movahedi AA, Ahmad F, Hakimelahi GH, Habibi-Rezaei M, Saboury AA, and Sheibani N. (2007) Formation of the Molten Globule-Like State during Prolonged Glycation of Human Serum Albumin. Biochemica. Biophysica. Acta 1770:933-942.

Safarian S, Bagheri F, Moosavi-Movahedi AA, Amanlo M, and Sheibani N. (2007) Competitive inhibitory effects of acetazolamide upon interactions with bovine carbonic anhydrase II. The Protein J. 26:371-381.

Scheef EA, Huang Q, Wang S, Sorenson CM, and Sheibani N. (2007). Isolation and characterization of corneal endothelial cells from wild type and thrombospondin-1 deficient mice. Mol. Vision 131:1483-1495.

Presentations:
2007 Yale University, Department of Pathology. “Isoform Specific Function of PECAM-1 in Angiogenesis.”

2007 FASEB Summer Research Conference, Hilton Tucson, Tucson, AZ- Thrombospondins and other Matricellular Proteins in Tissue Organization and Homeostasis. “Thrombospondin-1 and Vascular Homeostasis”

Igor Slukvin:

Invited book chapters

Vodyanik M. and Slukvin I. Directed differentiation of human embryonic Stem Cells to dendritic cells. Methods Mol Biol. 2007; 407: 275-294

Vodyanik, M. A., and Slukvin I. 2007. Hematoendothelial differentiation of human embryonic Stem Cells. In Current Protocols in Cell Biology, Vol. 36. John Wiley & Sons, Inc., Somerset, New Jersey, p. 23.26.21-23.26.28.

Invited Presentations
September 7, 2005 Duke University, GU Cancer Immunotherapy Program, Durham, NC

September 23, 2005 Northern Illinois University, Dekalb, IL

October 3, 2005 BC Cancer Center, Vancouver, BC Canada

October 11, 2006 University of Connecticut Health Center, Farmington, CT

April 18, 2007 2nd Wisconsin Stem Cell Symposium, Madison, WI

April 24, 2007 University of California Riverside, Riverside, CA

January 29-February 2, 2008 First International Symposium on Human Embryonic Stem Cell Research, Paris, France

Paul Sondel:

Sondel PM, Hank JA, Albertini MR, Gillies SD. Novel Strategies for Cytokine Administration via Targeting. In: Cytokines in the Genesis and Treatment of Cancer. Caligiuri MA, Lotze MT (eds). Humana Press, Totowa NJ; 2007, pp.399-422

Mahvi DM, Henry MB, Albertini MR, Weber S, Meredith K, Schalch H, Rakhmilevich A, Hank JA, Sondel PM. Intratumoral injection of IL-12 plasmid DNA: Results of a phase I/IB clinical trial. Cancer Gene Therapy, 14, 717-723, 2007.

Cassaday RD, Sondel PM, King DM, Macklin MD, Gan J, Warner TF, Zuleger CL, Bridges AJ, Schalch HG, Kim KM, Hank JA, Mahvi DM, Albertini MR. A Phase I study of Immunization Using Particle-Mediated Epidermal Delivery of Genes for GP-100 and GM-CSF into Uninvolved Skin of Melanoma Patients. Clinical Cancer Research,13:540-549, 2007.

Gilman AL, Ozkaynak F, Matthay K, Krailo M, Yu A, Gan J, Sternberg A, Hank J, Seeger R, Reaman G, Sondel PM. Phase I Study of ch14.18 with GM-CSF and IL-2 in Children with Neuroblastoma Following Autologous Bone Marrow Transplant or Stem Cell Rescue: A Report from the Children’s Oncology Group. Submitted, 2007

Wu Q, Buhtoiarov IN, Sondel PM, Rakhmilevich AL, Ranheim. Effective Immunotherapy in a mouse model of chronic lymphocytic leukemia by CD40-activated macrophages. Submitted, 2007.

Rakhmilevich AL, Buhtoiarov IN, Malkovsky M, Sondel PM. CD40 ligation in vivo can induce T cell independent antitumor effects even against immunogenic tumors. Submitted 2007.

Buhtoiarov IN, Sondel PM, Eickhoff JC, Rakhmilevich AL. Macrophages are essential for antitumor effects against weakly immunogenic murine tumors induced by class B CpG-ODN. Immunology, 120:412-423, 2007.

Neal ZC, Sondel PM, Bates MK, Gillies SD, Herweijer H. Flt3-L gene therapy enhances immunocytokine-mediated antitumor effects and induces long-term memory. Cancer Immunology and Immunotherapy. 56:1765-1764, 2007.

Khawli LA, Tu AL, Sachsman A, Buhtoiarov IN, Sondel PM, Epstein AL. Targeted CpG for the Immunotherapy of Solid Tumors. Submitted 2007.

Johnson E, Dean SM, Sondel PM. Antibody Based Immunotherapy in High Risk Neuroblastoma. Expert Reviews in Molecular Medicine; In Press, 2007.

Johnson EE, Lum HD, Rakhmilevich AL, Schmidt BE, Furlong M, Buhtoiarov IN, Hank JA, Raubitschek A, Colcher D, Reisfeld RA, Gillies SD, Sondel PM. Intratumoral Immunocytokine Treatment Results in Enhanced Antitumor Activity. Submitted, 2007.

Grupp S, Verneris M, Sondel PM, Cooper LJN. Immunotherapy for Pediatric Cancer. Submitted. 2007

Meany HJ, Seibel N, Sun J, Finklestein JZ, Sato J, Kelleher J, Sondel PM, Reaman G. Phase II Trial of Recombinant Tumor Necrosis Factor- in Combination with Dactinomycin in Children with Recurrent Wilms Tumor. Submitted 2007

Buhtoiarov IN, Rakhmilevich AL, Lanier LL, Sondel PM. Naïve mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules. Submitted 2008

Gary Splitter:

Swartz, T.E., Tseung, T-S., Frederickson, M.A., Paris, G., Rajashekara, G. Kim, J-G., Mudgett, M.B., Splitter, G., Goldbaum, F., Briggs, W.R., and Bogomolni, R.A. Light-activated LOV-histidine kinases: a new bacterial photoreceptor family. Science, 317:1090-3, 2007.

Rambow-Larsen, A.A., Rajashekara, G., Petersen, E. and Splitter, G. Identification of a second LuxR homolog, BlxR, involved in quorum sensing in Brucella melitensis. J. Bact., Manuscript in Press.

Rajashekara, G., Krepps, M., Petersen, E., Covert, J., Eskra, L., and Splitter, G. Genomic island-2 of B. melitensis is a major virulence determinant: Systematic and functional analyses of a pathogenicity island. Manuscript in Review.

Mathison, A. and Splitter, G. Highly homologous Brucella spp. infections elicit macrophage transcript profiles with select species specific host defense mechanisms. Manuscript in Review.

Mathison, A., Harms, J. and Splitter, G. Knockdown of Fc?RI impairs Brucella melitensis and Brucella neotomae, but not Brucella ovis infection of macrophages. Manuscript in Review.

Dandan Sun:

Luo J, Wang Y, Chen H, Kintner DB, Cramer SW, Gerdts JK, Chen X, Shull GE, Philipson KD, Sun D A concerted roleof Na+-K+-Cl- cotransproter and Na+/Ca2+ exchanger in ischemic damage. J. Cereb.Blood Flow Metab. 3-Oct 2007

Luo J, Kintner DB, Shull GE, Sun D ERK1/2-p90RSK-mediated Phosphorylation of Na+/H+ Exchanger Isoform 1, a role in ishcemic Neuronal death. J. Biochem. 282(38): 28274-84, 2007

Chen H, Kintner DB, Jones M, Baba A, Matsuda T, Kiedrowski L, Sun D. AMPA-mediated excitotoxicity in oligodendrocytes:role for Na+-K+-Cl- cotransport and reversal of Na+/Ca2+ exchanger . J. Neurochem. 10:1783–1795, 2007

Luo J, Wang Y, Chen X, Chen H, Kintner DB, Shull GE, Philipson KD, Sun D Increased tolerance to ischemic Neuronal damage by knockdown of Na+-Ca2+ exchanger isoform1. In: Sodium-Calcium exchange and the plasma membrane Ca2+-ATPase in cell function. Fifth International Conference . Annals of N.Y. Acad. Sci. 1099:292-305, 2007. Eds: A. Herchuelz, M.P. Blaustein, J. Lytton, K.D. Philipson

Luo J, Sun D. Physiology and pathophysiology of Na+/H+ exchange isoform 1 in central nervous system. Curr Neurovasc Res. 4(3):205-15. 2007

Kintner DB, Luo J, Gerdts J, Ballard AJ, Shull GE, Sun D. Role of Na+-K+-Cl- cotransport and Na+/Ca2+ exchange in mitochondrial dysfunction in astrocytes following in vitro ischemia. Am J Physiol Cell Physiol. 292(3):C1113-22, 2007

Kintner DB, Wang Y, Sun D. The role of membrane ion transport proteins in cerebral ischemic damage. Frontiers in Bioscience 12,762-770, 2007

M Suresh:

Xu, J., J. Cai, B. Anderson, B. Wagner, R. Albrecht, S. F. Peek, M. Suresh, and B. J. Darien (2007) Cloning and characterization of recombinant equine P-selectin. Vet. Immunol. Immunopathol. 116(3-4):115-130.

Singh, A., M. Wuthrich, B. Klein, and M. Suresh (2007) Indirect regulation of CD4 T-cell responses by TNF receptors during an acute viral infection. J. Virol. 81(12):6502-6512.

Hogan, L. H., D. O. Co, J. Karman, E. Heninger, M. Suresh, and M. Sandor (2007) Virally activated CD8 T cells home to Mycobacterium bovis BCG-induced granulomas, but enhance anti-microbial protection only in immunodeficient mice. Infect. Imm. (75(3):1154-66.

Tewari, K., Y. Nakayama, and M. Suresh (2007) Role of direct effects of IFN-γ on T cells in the regulation of CD8+ T cell homeostasis. J. Immunol. 179(4):2115-2125.

Shamim, M., S. Nanjappa, A. Singh, E. Plisch, S. LeBalanc, J. Svaren, C. Seroogy, and M. Suresh (2007) Cbl-b regulates antigen-induced TCR down regulation and IFN-γ production by effector CD8 T cells without affecting functional avidity. J. Immunol. 179(11):7233-43.

Singh, A and M. Suresh (2007) A Role for TNF in limiting the duration of CTL effector phase and magnitude of CD8 T-cell memory. J. Leuk. Biol. 82(5):1201-11.

Shi, L. Z., N. G. Faith, Y. Nakayama, M. Suresh, H. Steinberg, and C. J. Czuprynski (2007) The Aryl Hydrocarbon Receptor Is Required for Optimal Resistance to Listeria monocytogenes Infection in Mice. J. Immunol. 179(10):6952-62.

Nanjappa, S., J. Walent, Michel Morre, and M. Suresh (2008) Effects of IL-7 on CD8 T cell memory are influenced by the timing of therapy. J. Clin. Invest. (Accepted for Publication).

Xu, J., J. Cai, S. F. Peek, M. Suresh, and B. J. Darien (2007). Characterization of equine P-selectin glycoprotein ligand-1 by using a specific monoclonal antibody. Vet. Immunol. Immunopathol. (Accepted for Publication).

Adel Talaat:

Ward SK, Hoye EA, Talaat AM. The global responses of Mycobacterium tuberculosis to physiological levels of copper. J Bacteriol. 2008 Feb 8; [Epub ahead of print]

Wu CW, Schmoller SK, Shin SJ, Talaat AM. Defining the stressome of Mycobacterium avium subsp. paratuberculosis in vitro and in naturally infected cows. J Bacteriol. 2007 Nov;189(21):7877-86. Epub 2007 Aug 10.

Hines ME 2nd, Stabel JR, Sweeney RW, Griffin F, Talaat AM, Bakker D, Benedictus G, Davis WC, de Lisle GW, Gardner IA, Juste RA, Kapur V, Koets A, McNair J, Pruitt G, Whitlock RH. Experimental challenge models for Johne's disease: a review and proposed international guidelines. Vet Microbiol. 2007 Jun 21;122(3-4):197-222. Epub 2007 Mar 27. Review.

Talaat AM, Ward SK, Wu CW, Rondon E, Tavano C, Bannantine JP, Lyons R, Johnston SA. Mycobacterial bacilli are metabolically active during chronic tuberculosis in murine lungs: insights from genome-wide transcriptional profiling. J Bacteriol. 2007 Jun;189(11):4265-74. Epub 2007 Mar 23.

Wu CW, Livesey M, Schmoller SK, Manning EJ, Steinberg H, Davis WC, Hamilton MJ, Talaat AM. Invasion and persistence of Mycobacterium avium subsp. paratuberculosis during early stages of Johne's disease in calves. Infect Immun. 2007 May;75(5):2110-9. Epub 2007 Feb 12.

Cho D, Shin SJ, Talaat AM, Collins MT. Cloning, expression, purification and serodiagnostic evaluation of fourteen Mycobacterium paratuberculosis proteins. Protein Expr Purif. 2007 Jun;53(2):411-20. Epub 2007 Jan 9.

Liu T, Ramesh A, Ma Z, Ward SK, Zhang L, George GN, Talaat AM, Sacchettini JC, Giedroc DP. CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator. Nat Chem Biol. 2007 Jan;3(1):60-8. Epub 2006 Dec 3.

David Watkins:

Chung C, Lee W, Loffredo JT, Burwitz B, Friedrich TC, Giraldo Vela JP, Napoe G, Rakasz EG, Wilson NA, Allison DB, Watkins DI. Not all cytokine-producing CD8+ T-cells suppress simian immunodeficiency virus replication. J. Virol., 2007 Feb: 81(3): 1517-23.

Queiroz AT, Santos LA, Moreau DR, Oliveira T, Watkins DI, Galvão-Castro B, Alcantara LC. Identification and characterization of previously described epitopes in HIV-1 subtypes B, C, F and BF in Brazil. Braz. J. Infect. Dis., 2007 Feb: 11(1): 27-30.

Loffredo, JT, Burwitz BJ, Rakasz EG, Spencer SP, Stephany JJ, Vela JP, Martin SR, Reed J, Piaskowski SM, Furlott J, Weisgrau KL, Rodrigues DS, Soma T, Napoé G, Friedrich TC, Wilson NA, Kallas EG, Watkins DI. The antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape. J. Virol., 2007 Mar: 81(6): 2624-34.

Sacha JB, Chung C, Rakasz EG, Spencer SP, Jonas AK, Bean AT, Lee W, Burwitz BJ, Stephany JJ, Loffredo JT, Allison DB, Adnan S, Hoji A, Wilson NA, Friedrich TC, Lifson JD, Yang OO, Watkins DI. Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression. J. Immunol., 2007 Mar: 178(5): 2746-54.

Friedrich TC, Valentine LE, Yant LJ, Rakasz EG, Piaskowski SM, Furlott JR, Weisgrau KL, Burwitz B, May GE, León EJ, Soma T, Napoe G, Capuano SV 3rd, Wilson NA, Watkins DI. Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication. J. Virol., 2007 Apr: 81(7): 3465-76.

Kawada M, Tsukamoto T, Yamamoto H, Takeda A, Igarashi H, Watkins DI, Matano T. Long-term control of simian immunodeficiency virus replication with central memory CD4+ T-cell preservation after nonsterile protection by a cytotoxic T-lymphocyte-based vaccine. J. Virol., 2007 May: 81(10): 5202-11.

Fuller DH, Shipley T, Allen TM, Fuller JT, Wu MS, Horton H, Wilson N, Widera G, Watkins DI. Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques. Virology, 2007 Aug: 364(2): 245-55.

Loffredo JT, Maxwell J, Qi Y, Glidden CE, Borchardt GJ, Soma T, Bean AT, Beal DR, Wilson NA, Rehrauer WM, Lifson JD, Carrington M, Watkins DI. Mamu-B*08-positive macaques control simian immunodeficiency virus replication. J. Virol., 2007 Aug: 81(16): 8827-32.

Kaizu M, Borchardt GJ, Glidden CE, Fisk DL, Loffredo JT, Watkins DI, Rehrauer WM. Molecular typing of major histocompatibility complex class I alleles in the Indian rhesus macaque which restrict SIV CD8+ T cell epitopes. ImmunoGenetics, 2007 Sep: 59(9): 693-703.

Maness NJ, Valentine LE, May GE, Reed J, Piaskowski SM, Soma T, Furlott J, Rakasz EG, Friedrich TC, Price DA, Gostick E, Hughes AL, Sidney J, Sette A, Wilson NA, Watkins DI. AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape. J. Exp. Med., 2007 Oct: 204(11): 2505-12.

Sacha JB, Chung C, Reed J, Jonas AK, Bean AT, Spencer SP, Lee W, Vojnov L, Rudersdorf R, Friedrich TC, Wilson NA, Lifson JD, Watkins DI. Pol-specific CD8+ T cells recognize SIV-infected cells prior to Nef-mediated major histocompatibility complex class I down-regulation. J. Virol., 2007 Nov: 81(21): 11703-12.

Loffredo JT, Friedrich TC, Leon EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, Beal DR, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, Wilson NA, Price DA, Kallas EG, Piontkivska H, Hughes AL, Sette A, Watkins DI. CD8 T Cells from SIV Elite Controller Macaques Recognize Mamu-B*08-Bound Epitopes and Select for Widespread Viral Variation. PLoS ONE, 2007 Nov: 2(11): e1152.

Valentine LE, Piaskowski SM, Rakasz EG, Henry NL, Wilson NA, Watkins DI. Recognition of Escape Variants in Elispot Does Not Always Predict CD8+ T-Cell Recognition of SIV-Infected Cells Expressing the Same Variant Sequences. J. Virol., 2008 Jan: 82(1):575-81.

Giraldo-Vela JP, Rudersdorf R, Chung C, Qi Y, Wallace LT, Bimber B, Borchardt GJ, Fisk DL, Glideen CE, Loffredo JT, Piaskowski SM, Furlott JR, Morales-Martinez JP, Wilson NA, Rehrauer WM, Lifson JD, Carrington M, Watkins DI. The Major Histocompatibility Complex class II alleles Mamu-DRB1*1003 and –DRB1*0306 are enriched in a cohort of SIV-infected rhesus macaque elite controllers. J. Virol., 2008 Jan: 82(2): 859-70.

Loffredo JT, Bean AT, Beal DR, Leon EJ, May GE, Piaskowski SM, Furlott JR, Reed J, Musani SK, Rakasz EG, Friedrich TC, Wilson NA, Allison DB, Watkins DI. Patterns of CD8+ Immunodominance May Influence the Ability of Mamu-B*08-positive Macaques to Naturally Control SIVmac239 Replication. J. Virol., 2007 Epub ahead of print.

Jon Woods:

Bohse ML and JP Woods. 2007. Expression and interstrain variability of the YPS3 gene of Histoplasma capsulatum. Eukaryotic Cell. 6: 609-615.

Zarnowski, R., M. Miyazaki, A. Dobrzyn, J.M. Ntambi, and JP Woods. 2007. Typing of Histoplasma capsulatum strains by fatty acid profile analysis. J.Med.Microbiol. 56: 788-797.

Bohse ML and JP Woods. 2007. RNA interference-mediated silencing of the YPS3 gene of Histoplasma capsulatum reveals virulence defects. Infect.Immun. 75: 2811-2817.

Zarnowski R, PA Connolly, LJ Wheat, and JP Woods. 2007. Production of extracellular proteolytic activity by Histoplasma capsulatum grown in Histoplasma-macrophage medium is limited to RFLP class 1 isolates. Diagn.Microbiol.Infect.Dis. 59: 39-47.

Zarnowski R, A Dobrzyn, JM Ntambi, and JP Woods. 2007. Neutral storage lipids of Histoplasma capsulatum: effect of culture age. Curr.Microbiol. In press.

Aravalli RN, S Hu, JP Woods, and JR Lokensgard. 2007. Histoplasma capsulatum yeast phase-specific protein Yps3p induces Toll-like receptor 2 signaling. Submitted.

Zarnowski R, KG Cooper, LS Brunold, J Calaycay, and JP Woods. 2007. Histoplasma capsulatum secreted -glutamyltransferase reduces iron by generating an efficient ferric reductant. Submitted.

Weixiong Zhong:

Aziz MH, Manoharan HT, Church DR, Dreckschmidt NE, Zhong W, Oberley TD, Wilding G, Verma AK. Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer. Cancer Res. 2007 Sep 15;67(18):8828-38.

Chaiswing L, Bourdeau-Heller JM, Zhong W, Oberley TD. Characterization of redox state of two human prostate carcinoma cell lines with different degrees of aggressiveness. Free Radic Biol Med. 2007 Jul 15;43(2):202-15. Epub 2007 Apr 10.

Elkahwaji JE, Zhong W, Hopkins WJ, Bushman W. Chronic bacterial infection and inflammation incite reactive hyperplasia in a mouse model of chronic prostatitis. Prostate. 2007 Jan 1;67(1):14-21.