Subhojit Roy, MD, PhD
- The UW Medical Foundation (UWMF) Professor of Pathology & Laboratory Medicine
Department of Pathology and Laboratory Medicine
Cell Biology of neuronal trafficking in physiology and neurodegenerative diseases
Cell Biology of neuronal trafficking in physiology and neurodegenerative diseases. The Roy lab is interested in the cell biology of neuronal trafficking in physiology and disease. A general approach in the lab is to develop simple cellular models of normal and abnormal biological phenotypes – using dissociated neurons, 3-D organoids, and induced pluripotent stem cells (iPSC's) – and test predictions from these models in brains. For a list of publications, please see: http://www.roylab.org/publications.html. Current projects include novel uses of CRISPR-Cas9 technology in cellular model-systems of neurodegenerative diseases, optogenetic approaches to study slow axonal transport, and use of iPSC’s to explore human cell biology. The lab has ongoing collaborations with researchers at the Wisconsin Institute for Discovery (WID), the Waisman Center, and other investigators at UW-Madison; and is located on modern, state of the art laboratory and office space overlooking lake Mendota (within the Wisconsin Institute for Medical Research or WIMR-II tower: WIMR-II-science-without-walls).